Brown University

Fetal Medicine @ Brown

The Warren Alpert Medical School of Brown University

Abdominal Wall Defects:
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The text below will, hopefully, answer some of the questions you may have regarding this condition. You can scroll down, or go directly to a specific question:

Underlined terms are explained in detail - just click on them. A medical review on this topic was recently published by Dr. Kurkchubasche in Medicine & Health/Rhode Island.


Gastroschisis (sometimes called "laparoschisis") means the presence of a hole in the abdominal wall of the fetus, through which loops of intestines (and sometimes stomach, liver and other organs) protrude. The term only applies to those conditions where the hole is located to the side of the umbilicus (umbilical cord); practically speaking, this hole is almost always to the left of the umbilical cord. Gastroschisis is not the same as Omphalocele, which refers to a hole in the abdominal wall in the belly button. Although both conditions appear the same (intestines protruding outside the abdomen), each condition has its own features. To learn more about omphalocele, click here. Abdominal wall defects can be detected by ultrasound from the third month of pregnancy on (14 to 15 weeks). As the pregnancy progresses, diagnosis becomes more accurate: loops of intestine can then be seen outside the abdomen, "floating" into the amniotic cavity (arrow).

If you would like to see other Images of gastroschisis, you can click here. However, be aware that some of these Images are graphic in nature, and may not be suitable for everyone. If you prefer, you can contact us for further information.


Gastroschisis occurs in approximately 1 of every 2,000 live births, making it a relatively "common" congenital anomaly. In fact, its incidence seems to be increasing in recent years, for reasons unknown. There seems to be a relationship with young maternal age, although it can occur at any age. At our institution, we treat 6-10 infants with gastroschisis every year.


Gastroschisis can be diagnosed with fairly good accuracy from the 14th week of gestation (3 months). It is now possible to intervene during pregnancy for a number of anomalies (see for example twin-to-twin transfusion syndrome). It would be tempting, therefore, to try and treat the fetus with gastroschisis before birth. However, extensive research has shown that patients with gastroschisis (and omphalocele) are best treated after they are born, and that most in utero interventions would be too risky for mother and child.

We can intervene in other ways, though: with advance knowledge of an abdominal wall defect, it is possible to change the plans for delivery of the baby. One can change the mode, place and time of delivery.

1. Mode of delivery

If intestines and other organs are outside the abdomen, it would seem logical that they would be at an increased risk of being damaged during normal delivery. Some have therefore advocated Cesarean section ("C-section") for all cases of gastroschisis and omphalocele. In fact, the risk of injury is only theoretical, and vaginal delivery does not put the baby at an increased risk of complications. For that reason, most (although not all) physicians now recommend normal delivery, even for gastroschisis, unless there are obstetrical reasons to proceed with a C-section.

2. Place of delivery

As long as he or she is inside the womb, the fetus with a gastroschisis is relatively well shielded from trauma and complications. After birth, however, the exposed intestines have to be protected from direct trauma, dehydration and infection. The baby can be safely transported to a treatment center, as long as certain precautions are taken. However, if the diagnosis of gastroschisis has been made beforehand, it would seem logical to have the baby be born directly in such a treatment center (i.e., a center with a neonatal intensive care unit and immediate access to a pediatric surgery service). Therefore, we generally recommend that, if you are pregnant with a fetus with gastroschisis or omphalocele, you plan to deliver in such a tertiary institution. Your care will likely be transferred to a Maternal-Fetal Medicine specialist at our institution, to facilitate the transition to peri- and postnatal care.

3. Time of delivery

One of the concerns with gastroschisis is that the exposed bowel becomes so damaged, that function is impaired and the baby may end up staying in the intensive care for a long time. It is known that many infants with gastroschisis have what appears to be damaged bowel, with very thick, rigid loops of intestines containing a "peel" (see picture). One of the theories for this peel "peel" and thickened intestinal wall in gastroschisis(and for the fact that some babies have little or no peel at all) is that prolonged exposure of the bowel to the amniotic fluid causes progressive damage. In other words, limiting the amount of time that the bowel is floating in this fluid (or even diluting that fluid by infusing sterile saline water inside the womb) could theoretically decrease the amount of peel and intestinal damage.

Many centers have therefore recommended early delivery (between 35 and 37 weeks of gestation, instead of the normal 40 weeks). Unfortunately, there are no good scientific studies proving the benefits of this. In fact, at our institution, we have reviewed all babies born with gastroschisis in the last 10 years, and have found no benefit at all of early delivery. For that reason, we recommend that your baby be born as close to term as possible.

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